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AAPS Pharmacokinetics, Pharmacodynamics and Drug Metabolism (PPDM)

Thursday, November 15

7:00 am – 8:15 am

Thursday Sunrise Sessions are Funded by a Grant from

Sunrise Session
ACPE #073-999-07-549-L04

Food products may contain protective or harmful effects on enzymes or transporters. Several notable examples are included in this sunrise session. Fruit juices and herbal products as well as nutrient supplements are part of food intake in every day life. The manner in which juices and herbal and nutraceutical products affect enzymes and transporters has not been fully characterized. This sunrise session will summarize the latest studies on these, and include other food stuff such as garlic and green tea effects. The pros and cons of the interactions are highlighted.

Moderators

K. Sandy Pang, Ph.D.
University of Toronto

Keith Hoffmaster, Ph.D.
Pfizer, Inc.

Juices, Enzymes and Transporters
David G. Bailey, Ph.D.
University of Western Ontario

Diet and Drug Interactions: Transporter-mediated Changes in Drug Disposition
Marilyn E. Morris, Ph.D.
University at Buffalo, SUNY

Dietary/Herbal Supplements and Nuclear Receptor Activation: Effects of CAR and PXR
Thomas K.H. Chang, Ph.D.
University of British Columbia

*Session tentatively scheduled to be recorded.

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