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Pharmacogenomics (PGx) Focus Group |
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Definition of Pharmacogenetics and Pharmacogenomics
Pharmacogenetics is the study of genetic causes of individual variations in drug
response; pharmacogenomics more broadly involves genome-wide analysis of the genetic
determinants of drug efficacy and toxicity. Primary candidate genes of interest
include those encoding for drug receptors, metabolizing enzymes, and transporters.
However, selection of optimal drug therapy may also involve disease susceptibility
genes indirectly affecting drug response. Moreover, pharmacogenomics includes the
identification of suitable targets for drug discovery and development.
Objectives
- Provide a forum for information exchange on topical developments in pharmacogenetics
and pharmacogenomics, using an interactive webpage designed for the focus group
(accessible to all AAPS members).
- Generate yearly theme issues in pharmacogenetics-pharmacogenomics in The AAPS
Journal.
- Establish a virtual journal in pharmacogenetics-pharmacogenomics with links to relevant
articles in all life sciences journals.
- Organizing symposia, workshops, roundtables, guest speaker programs, etc.
- Develop a knowledge base in pharmacogenetics and pharmacogenomics in the form of
relational databases, key references, links to relevant sites, etc, accessible on
the focus group webpage.
- Facilitate communication between academia, biotechnology/genomics firms, and regulatory
agencies.
- Provide a forum for advertisement by pharmaceutical companies with pharmacogenomics
interests.
JOIN THE PHARMACOGENOMICS (PGx) FOCUS GROUP
To join the Pharmacogenomics (PGx) Focus Group, click
here.
PGx Highlights – A PGx Focus Group Newsletter
PGx Resource
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